Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | BRAF | P15056 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | RHOA | P61586 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13203824 | 0.89 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPTMEN1KMT2ATP53 | |
| SCHEMBL10113291 | 0.89 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPTMEN1KMT2ATP53 | |
| SCHEMBL10133141 | 0.89 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPTMEN1KMT2ATP53 | |
| SCHEMBL10113283 | 0.87 | SMN1; SMN2 (0.48) | SMN1; SMN2MAPTMEN1KMT2ATP53 | |
| SCHEMBL13203822 | 0.87 | SMN1; SMN2 (0.48) | SMN1; SMN2MAPTMEN1KMT2ATP53 | |
| SCHEMBL10133413 | 0.86 | KMT2A (0.58) | MAPTMEN1KMT2ATP53NPY5R | |
| SCHEMBL10114295 | 0.86 | KMT2A (0.58) | MAPTMEN1KMT2ATP53NPY5R | |
| SCHEMBL10113273 | 0.85 | NPY5R (0.53) | SMN1; SMN2MAPTNPY5RLMNAGAA | |
| SCHEMBL14424628 | 0.85 | ALDH1A1 (0.56) | SMN1; SMN2NPY5RLMNAGAAUSP2 | |
| SCHEMBL10114576 | 0.85 | ALDH1A1 (0.56) | SMN1; SMN2NPY5RLMNAGAAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8115027-B2 | NPY Y5 antagonist | SHIONOGI & CO., LTD. (JP) | 2012-02-14 | — | — | US | disclosed |
| US-20100292500-A1 | NPY Y5 ANTAGONIST | KAWANISHI YASUYUKI | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292500-A1 | NPY Y5 ANTAGONIST | NPY5R, NPY1R, NPY2R | SMN1; SMN2 2197/4885MAPT 3367/4885MEN1 2932/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.