Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28152084 | 0.98 | NPC1 (0.59) | NPC1POLBMAPTMEN1KMT2A | |
| SCHEMBL18789747 | 0.86 | MEN1 (0.50) | NPC1POLBMAPTMEN1KMT2A | |
| SCHEMBL28173261 | 0.85 | MEN1 (0.49) | NPC1POLBMAPTMEN1KMT2A | |
| SCHEMBL28112587 | 0.83 | NPC1 (0.58) | NPC1POLBMAPTMEN1KMT2A | |
| SCHEMBL27768402 | 0.78 | KMT2A (0.50) | NPC1POLBMAPTMEN1KMT2A | |
| SCHEMBL212127 | 0.77 | KDR (0.54) | NPC1POLBMAPTRAB9AALDH1A1 | |
| SCHEMBL3147770 | 0.77 | NPC1 (0.63) | NPC1POLBMAPTMEN1KMT2A | |
| SCHEMBL31084267 | 0.77 | NPC1 (0.67) | NPC1POLBMAPTMEN1KMT2A | |
| SCHEMBL7262444 | 0.77 | NPC1 (0.62) | NPC1POLBMAPTMEN1KMT2A | |
| SCHEMBL7774453 | 0.77 | NPC1 (0.67) | NPC1POLBMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110312511-A | pharmaceutical composition | 大鹏药品工业株式会社 | 2019-10-08 | — | — | CN | claimed |
| CN-105814040-B | The condensed 1,4- dihydro two of inhibitor as thermal excited transcryption factor 1 dislikes ene derivative | 癌症研究科技有限公司 | 2019-07-30 | — | — | CN | claimed |
| CN-110035995-A | MAChR M4Positive allosteric modulators | 范德比尔特大学 | 2019-07-19 | — | — | CN | claimed |
| CN-106565682-B | Substituted indole expires ketone derivatives and application thereof | 沈阳药科大学 | 2019-07-16 | — | — | CN | claimed |
| CN-106467541-B | Substituted quinolone analog derivative or its pharmaceutically acceptable salt or stereoisomer and its Pharmaceutical composition and application | 暨南大学 | 2019-04-05 | — | — | CN | claimed |
| CN-108997214-A | It is happy to cut down for Buddhist nun's intermediate and its preparation and the happy preparation cut down for Buddhist nun | 成都地奥制药集团有限公司 | 2018-12-14 | — | — | CN | claimed |
| CN-105985335-B | Hydroxamic acid compound, preparation method and its usage | 成都地奥九泓制药厂 | 2018-06-08 | — | — | CN | claimed |
| CN-107614489-A | Methanesulfonic acid salt of acylthiourea compound, crystal thereof, and process for producing them | 大鹏药品工业株式会社 | 2018-01-19 | — | — | CN | claimed |
| CN-107072985-A | Therapeutic inhibiting compound | 莱福斯希医药公司 | 2017-08-18 | — | — | CN | claimed |
| CN-106565682-A | Substituted indolinone derivative and application thereof | 沈阳药科大学 | 2017-04-19 | — | — | CN | claimed |
| CN-106458912-A | Bicyclic fused heteroaryl or aryl compounds and their use as IRAK4 mimetics | 辉瑞公司 | 2017-02-22 | — | — | CN | claimed |
| EP-3812040-B1 | COMPLEXES | JOHNSON MATTHEY PLC (GB) | 2023-01-11 | — | — | EP | disclosed |
| CN-110483482-A | Indoline -1- Carbox amide, preparation method and its in application pharmaceutically | BEIJING INNOCARE PHARMA TECH CO LTD | 2019-11-22 | — | — | CN | disclosed |
| CN-104788430-B | The treatment method of pyrazole derivatives calcium release activation calcium channel modulators and non-small cell lung cancer | 理森制药股份公司 | 2019-10-22 | — | — | CN | disclosed |
| CN-110312511-A | pharmaceutical composition | 大鹏药品工业株式会社 | 2019-10-08 | — | — | CN | disclosed |
| WO-2010130034-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-11-18 | — | — | WO | disclosed |
| CN-101203142-A | Aromatic amides and ureas and their uses as sweet and/or delicate flavor modifiers, flavouring agents and taste enhancers | SENOMYX INC (US) | 2008-06-18 | — | — | CN | disclosed |
| US-20070238734-A1 | JNK INHIBITORS | SANOLI-AVENTIS (FR) | 2007-10-11 | — | — | US | disclosed |
| US-7265130-B2 | NPY Y5 antagonist | SHIONOGI & CO., LTD. (JP) | 2007-09-04 | — | — | US | disclosed |
| CN-1478078-A | Nitrogen-containing aromatic ring derivatives | ������������ʽ���� | 2004-02-25 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070238734-A1 | JNK INHIBITORS | MAP3K7, MAPKAPK2, MAPK7 | NPC1 1098/4885POLB 2141/4885MAPT 751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.