Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10133710 | 0.88 | MAPK14 (0.53) | NPY5RMAPK14ALDH1A1NPC1RAB9A | |
| SCHEMBL13203799 | 0.88 | MAPK14 (0.53) | NPY5RMAPK14ALDH1A1NPC1RAB9A | |
| SCHEMBL13203859 | 0.86 | NPY5R (0.48) | NPY5RMAPK14ALDH1A1NPC1RAB9A | |
| SCHEMBL10113330 | 0.86 | NPY5R (0.48) | NPY5RMAPK14ALDH1A1NPC1RAB9A | |
| SCHEMBL10133383 | 0.85 | MAPK14 (0.47) | MAPK14ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10113341 | 0.83 | NPC1 (0.57) | NPY5RALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13203865 | 0.83 | NPC1 (0.57) | NPY5RALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12882378 | 0.79 | NPY5R (0.48) | NPY5RMAPK14ALDH1A1NPC1RAB9A | |
| SCHEMBL14424102 | 0.79 | MAPK14 (0.55) | NPY5RMAPK14ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL10113215 | 0.79 | ALDH1A1 (0.70) | NPY5RMAPK14ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8115027-B2 | NPY Y5 antagonist | SHIONOGI & CO., LTD. (JP) | 2012-02-14 | — | — | US | disclosed |
| US-20100292500-A1 | NPY Y5 ANTAGONIST | KAWANISHI YASUYUKI | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292500-A1 | NPY Y5 ANTAGONIST | NPY5R, NPY1R, NPY2R | NPY5R 1/4885MAPK14 1392/4885ALDH1A1 4599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.