Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14424742 | 1.00 | ALDH1A1 (0.48) | ALDH1A1EPHX2NPY5RMAPTSMN1; SMN2 | |
| SCHEMBL13144983 | 0.88 | MAPT (0.50) | ALDH1A1EPHX2NPY5RMAPTSMN1; SMN2 | |
| SCHEMBL13204166 | 0.88 | MAPT (0.50) | ALDH1A1EPHX2NPY5RMAPTSMN1; SMN2 | |
| SCHEMBL10114327 | 0.88 | MAPT (0.50) | ALDH1A1EPHX2NPY5RMAPTSMN1; SMN2 | |
| SCHEMBL278192 | 0.88 | MAPT (0.50) | ALDH1A1EPHX2NPY5RMAPTSMN1; SMN2 | |
| SCHEMBL11936567 | 0.88 | MAPT (0.50) | ALDH1A1EPHX2NPY5RMAPTSMN1; SMN2 | |
| SCHEMBL10114387 | 0.88 | MAPT (0.50) | ALDH1A1EPHX2NPY5RMAPTSMN1; SMN2 | |
| SCHEMBL10133980 | 0.88 | MAPT (0.50) | ALDH1A1EPHX2NPY5RMAPTSMN1; SMN2 | |
| SCHEMBL13203694 | 0.88 | ALDH1A1 (0.63) | ALDH1A1EPHX2NPY5RMAPTSMN1; SMN2 | |
| SCHEMBL10113057 | 0.88 | ALDH1A1 (0.63) | ALDH1A1EPHX2NPY5RMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8115027-B2 | NPY Y5 antagonist | SHIONOGI & CO., LTD. (JP) | 2012-02-14 | — | — | US | disclosed |
| US-20100292500-A1 | NPY Y5 ANTAGONIST | KAWANISHI YASUYUKI | 2010-11-18 | — | — | US | disclosed |
| US-7781461-B2 | NPY Y5 antagonist | KAWANISHI YASUYUKI | 2010-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292500-A1 | NPY Y5 ANTAGONIST | NPY5R, NPY1R, NPY2R | ALDH1A1 4599/4885EPHX2 2527/4885NPY5R 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.