Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORA | P35398 | 1/20 | 0.51 |
| ▸ | RORC | P51449 | 1/20 | 0.51 |
| ▸ | RORB | Q92753 | 1/20 | 0.51 |
| ▸ | PIK3CG | P48736 | 10/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 8/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20118022 | 0.86 | RORA (0.47) | RORARORCRORBPIK3CGPIK3CA | |
| SCHEMBL1940303 | 0.85 | RORA (0.48) | RORARORCRORBPIK3CGPIK3CA | |
| SCHEMBL12197706 | 0.83 | RORA (0.54) | RORARORCRORBPIK3CGPIK3CA | |
| SCHEMBL7065705 | 0.82 | MEN1 (0.47) | RORARORCRORBPIK3CGPIK3CA | |
| SCHEMBL14519868 | 0.82 | RORA (0.47) | RORARORCRORBPIK3CGPIK3CA | |
| SCHEMBL12229089 | 0.82 | RORA (0.51) | RORARORCRORBPIK3CGPIK3CA | |
| SCHEMBL6101006 | 0.81 | RORA (0.50) | RORARORCRORBPIK3CGPIK3CA | |
| SCHEMBL4854398 | 0.80 | PIK3CG (0.50) | RORARORCRORBPIK3CGPIK3CA | |
| SCHEMBL10125972 | 0.80 | PIK3CG (0.57) | RORARORCRORBPIK3CGPIK3CA | |
| SCHEMBL41794 | 0.80 | PIK3CG (0.59) | RORARORCRORBPIK3CGPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012003476-A2 | HAPTEN CONJUGATES FOR TARGET DETECTION | VENTANA MEDICAL SYSTEMS, INC. (US) | 2012-01-05 | — | — | WO | disclosed |