Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.45 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.43 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SCN4A | P35499 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4397747 | 0.81 | SCN4A (0.49) | KDM4ESCN4A | |
| SCHEMBL3524491 | 0.81 | SCN4A (0.49) | KDM4ESCN4A | |
| SCHEMBL3830601 | 0.81 | S1PR5 (0.40) | S1PR1S1PR5FUCA1ALDH1A1CACNA1G | |
| SCHEMBL5260659 | 0.79 | DRD4 (0.46) | ALDH1A1SCN4A | |
| SCHEMBL5256067 | 0.79 | DRD4 (0.46) | ALDH1A1SCN4A | |
| SCHEMBL1995214 | 0.78 | SCN4A (0.47) | ALDH1A1SCN4A | |
| SCHEMBL25354555 | 0.76 | S1PR5 (0.50) | S1PR1S1PR5HTR4FUCA1FAAH | |
| SCHEMBL25354551 | 0.76 | S1PR5 (0.50) | S1PR1S1PR5HTR4FUCA1FAAH | |
| SCHEMBL2846768 | 0.74 | CACNA1B (0.53) | KCNH2 | |
| SCHEMBL4801694 | 0.74 | FUCA1 (0.53) | S1PR1S1PR5HTR4FUCA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7932246-B2 | Histone deacetylase inhibitors | CHROMA THERAPEUTICS LTD. (GB) | 2011-04-26 | — | — | US | disclosed |
| EP-1881977-B1 | HISTONE DEACETYLASE INHIBITORS | CHROMA THERAPEUTICS LTD (GB) | 2011-01-05 | — | — | EP | disclosed |