Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4397747 | 0.85 | SCN4A (0.49) | SCN4AMEN1KMT2AACHEPOLB | |
| SCHEMBL3524491 | 0.85 | SCN4A (0.49) | SCN4AMEN1KMT2AACHEPOLB | |
| SCHEMBL3830601 | 0.80 | S1PR5 (0.40) | SCN4AALDH1A1 | |
| SCHEMBL1013388 | 0.78 | S1PR1 (0.45) | SCN4AALDH1A1 | |
| SCHEMBL5260659 | 0.78 | DRD4 (0.46) | SCN4AALDH1A1DRD2DRD4 | |
| SCHEMBL5256067 | 0.78 | DRD4 (0.46) | SCN4AALDH1A1DRD2DRD4 | |
| SCHEMBL12384460 | 0.76 | ACHE (0.57) | MEN1KMT2AACHEALDH1A1SIGMAR1 | |
| SCHEMBL9920488 | 0.76 | ACHE (0.57) | MEN1KMT2AACHEALDH1A1SIGMAR1 | |
| SCHEMBL9920183 | 0.76 | ACHE (0.57) | MEN1KMT2AACHEALDH1A1SIGMAR1 | |
| SCHEMBL2320052 | 0.75 | ACHE (0.55) | ACHEALDH1A1SIGMAR1BCHEDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2338888-A1 | Imidazopyridine derivatives as JAK inhibitors | Almirall, S.A. (ES) | 2011-06-29 | — | — | EP | disclosed |