⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1651586 | 0.50 | — | — | |
| SCHEMBL235060 | 0.50 | — | — | |
| Hydrochloric Acid SCHEMBL23295202 | 0.47 | — | — | |
| SCHEMBL515026 | 0.44 | — | — | |
| SCHEMBL570870 | 0.44 | — | — | |
| SCHEMBL108935 | 0.42 | — | — | |
| SCHEMBL5573422 | 0.40 | — | — | |
| SCHEMBL992571 | 0.40 | — | — | |
| SCHEMBL13719381 | 0.31 | — | — | |
| SCHEMBL4550531 | 0.25 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 209 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1542692-B1 | AMINOPYRIMIDINE DERIVATIVES FOR USE AS VANILLOID RECEPTOR LIGANDS FOR THE TREATMENT OF PAIN | AMGEN INC (US) | 2011-01-05 | — | — | EP | claimed |
| EP-2270006-A1 | Pyridazine derivatives useful as vanilloid receptor ligands | Amgen, Inc (US) | 2011-01-05 | — | — | EP | claimed |
| US-7524874-B2 | Vanilloid receptor ligands and their use in treatments | AMGEN INC. (US) | 2009-04-28 | — | — | US | claimed |
| US-7439360-B2 | Vanilloid receptor ligands and their use in treatments | AMGEN INC. (US) | 2008-10-21 | — | — | US | claimed |
| US-7396831-B2 | Vanilloid receptor ligands and their use in treatments | AMGEN INC. (US) | 2008-07-08 | — | — | US | claimed |
| US-7390907-B2 | Vanilloid receptor ligands and their use in treatments | AMGEN INC. (US) | 2008-06-24 | — | — | US | claimed |
| EP-1910273-A2 | 10-SUBSTITUTED TETRACYCLINES AND METHODS OF USE THEREOF | Paratek Pharmaceuticals, Inc. (US) | 2008-04-16 | — | — | EP | claimed |
| US-20080070096-A1 | Proton Conducting Copolymers | STICHTING ENERGIEONDERZOEK CENTRUM NEDERLAND (NL) | 2008-03-20 | — | — | US | claimed |
| US-7332511-B2 | Vanilloid receptor ligands and their use in treatments | AMGEN INC. (US) | 2008-02-19 | — | — | US | claimed |
| EP-1778762-B1 | PROTON CONDUCTING COPOLYMERS | STICHTING ENERGIE (NL) | 2007-12-19 | — | — | EP | claimed |
| WO-2004014871-A1 | VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS | AMGEN INC. (US) | 2004-02-19 | — | — | WO | claimed |
| WO-2003099284-A1 | AMINO-PYRIDINE, -PYRIDINE AND PYRIDAZINE DERIVATIVES FOR USE AS VANILLOID RECEPTOR LIGANDS FOR THE TREATMENT OF PAIN | AMGEN INC. (US) | 2003-12-04 | — | — | WO | claimed |
| CN-1127490-C | As 5-HT1A1, 4-bifunctional cyclohexane derivatives of receptor ligands | PF MEDICAMENT (FR) | 2003-11-12 | — | — | CN | claimed |
| US-20030195201-A1 | Vanilloid receptor ligands and their use in treatments | AMGEN INC. | 2003-10-16 | — | — | US | claimed |
| WO-2003049702-A2 | VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS | AMGEN INC. (US) | 2003-06-19 | — | — | WO | claimed |
| EP-1023273-B1 | CYCLOHEXANE DERIVATIVES DIFUNCTIONALISED IN 1,4 AS LIGANDS OF 5HT1A RECEPTORS | PF MEDICAMENT (FR) | 2002-06-05 | — | — | EP | claimed |
| EP-0794949-B1 | NOVEL 3,5-DIOXO-(2H,4H)-1,2,4-TRIAZINE DERIVATIVES, THEIR PREPARATION AND USE AS DRUGS | PF MEDICAMENT (FR) | 1998-07-29 | — | — | EP | claimed |
| EP-0794949-A1 | NOVEL 3,5-DIOXO-(2H,4H)-1,2,4-TRIAZINE DERIVATIVES, THEIR PREPARATION AND USE AS DRUGS | PIERRE FABRE MEDICAMENT (FR) | 1997-09-17 | — | — | EP | claimed |
| WO-1996016949-A1 | NOVEL 3,5-DIOXO-(2H,4H)-1,2,4-TRIAZINE DERIVATIVES, THEIR PREPARATION AND USE AS DRUGS | PIERRE FABRE MEDICAMENT (FR) | 1996-06-06 | — | — | WO | claimed |
| US-3940391-A | HERBICIDE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-02-24 | — | — | US | claimed |