⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL935607 | 0.95 | CYP1A2 (0.39) | — | |
| Hydrochloric Acid SCHEMBL9551436 | 0.93 | CYP1A2 (0.38) | — | |
| SCHEMBL19839765 | 0.93 | CYP1A2 (0.42) | — | |
| SCHEMBL2992722 | 0.93 | CYP1A2 (0.42) | — | |
| Hydrochloric Acid SCHEMBL28005032 | 0.91 | CYP1A2 (0.41) | — | |
| SCHEMBL17610176 | 0.91 | — | — | |
| SCHEMBL4465183 | 0.83 | BPTF (0.47) | — | |
| SCHEMBL2821690 | 0.81 | CYP2C19 (0.41) | — | |
| Hydrochloric Acid SCHEMBL28019382 | 0.81 | BPTF (0.46) | — | |
| SCHEMBL28146431 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118632841-A | Heterocyclic compounds for the treatment of cancer | 阿提奥斯医药有限公司 | 2024-09-10 | — | — | CN | claimed |
| EP-4661875-A1 | COMPOUNDS AND COMPOSITIONS USEFUL AS DEGRADERS OF MK2 KINASE | Celgene Corporation (US) | 2025-12-17 | — | — | EP | disclosed |
| CN-118632841-A | Heterocyclic compounds for the treatment of cancer | 阿提奥斯医药有限公司 | 2024-09-10 | — | — | CN | disclosed |
| WO-2024167950-A1 | COMPOUNDS AND COMPOSITIONS USEFUL AS DEGRADERS OF MK2 KINASE | CELGENE CORPORATION (US) | 2024-08-15 | — | — | WO | disclosed |
| CN-108884071-B | Condensed ring based azetidinyl triazole derivative, preparation method and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2021-05-14 | — | — | CN | disclosed |
| CN-108884071-B | Condensed ring based azetidinyl triazole derivative, preparation method and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2021-05-14 | — | — | CN | disclosed |
| CN-108884071-B | Condensed ring based azetidinyl triazole derivative, preparation method and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2021-05-14 | — | — | CN | disclosed |
| CN-108884071-A | Condensed ring based azetidinyl triazole derivative, preparation method and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2018-11-23 | — | — | CN | disclosed |
| EP-2272858-A2 | HCV inhibitors comprising beta amino acids and their uses | Novartis AG (CH) | 2011-01-12 | — | — | EP | disclosed |