Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 3/20 | 0.47 |
| ▸ | PLD1 | Q13393 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP4 | P49662 | 1/20 | 0.44 |
| ▸ | CASP5 | P51878 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 4/20 | 0.42 |
| ▸ | HTR3B | O95264 | 4/20 | 0.42 |
| ▸ | HTR3A | P46098 | 4/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 4/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HTR2C | P28335 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28019382 | 0.98 | BPTF (0.46) | BPTFPLD1CASP1CASP4CASP5 | |
| SCHEMBL17610176 | 0.87 | — | — | |
| SCHEMBL1013538 | 0.83 | — | — | |
| SCHEMBL935607 | 0.83 | CYP1A2 (0.39) | CASP1CASP4CASP5HRH4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9551436 | 0.81 | CYP1A2 (0.38) | CASP1CASP4CASP5HRH4ALDH1A1 | |
| SCHEMBL19839765 | 0.81 | CYP1A2 (0.42) | CASP1CASP4CASP5HRH4ALDH1A1 | |
| SCHEMBL2992722 | 0.81 | CYP1A2 (0.42) | CASP1CASP4CASP5HRH4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28005032 | 0.79 | CYP1A2 (0.41) | CASP1CASP4CASP5HRH4ALDH1A1 | |
| SCHEMBL2821690 | 0.78 | CYP2C19 (0.41) | ALDH1A1CYP1A2MEN1CYP2C19KMT2A | |
| SCHEMBL5830533 | 0.78 | CNR2 (0.32) | ALDH1A1KDM4ECYP1A2HSD17B10CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118852137-A | Triazole piperazine compound and preparation method and application thereof | 山东大学深圳研究院 | 2024-10-29 | — | — | CN | claimed |
| CN-115551867-B | Fused tricyclic compounds, pharmaceutical compositions and uses thereof | 劲方医药科技(上海)有限公司 | 2024-02-20 | — | — | CN | claimed |
| US-20230203060-A1 | FUSED TRICYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | GENFLEET THERAPEUTICS (SHANGHAI) INC. (CN) | 2023-06-29 | — | — | US | claimed |
| EP-4159739-A1 | FUSED TRICYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | Genfleet Therapeutics (Shanghai) Inc. (CN) | 2023-04-05 | — | — | EP | claimed |
| CN-115551867-A | Fused tricyclic compound, pharmaceutical composition and application thereof | 劲方医药科技(上海)有限公司 | 2022-12-30 | — | — | CN | claimed |
| WO-2021239058-A1 | FUSED TRICYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2021-12-02 | — | — | WO | claimed |
| CN-111499640-A | Chiral resolution method of piperazinotriazole derivatives | 上海医药工业研究院 | 2020-08-07 | — | — | CN | claimed |
| EP-2881395-B1 | PIPERAZINOTRIAZOLE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF IN DRUG PREPARATION | SHANGHAI INST MATERIA MEDICA CAS (CN) | 2018-09-05 | — | — | EP | claimed |
| CN-103570725-B | Piperazidinoltriazole compound as well as preparation method and application thereof | 中国科学院上海药物研究所 | 2017-03-22 | — | — | CN | claimed |
| US-20150166544-A1 | PIPERAZINOTRIAZOLE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF IN DRUG PREPARATION | SHANGHAI ACEBRIGHT PHARMACEUTICALS CO., LTD. (CN) | 2015-06-18 | — | — | US | claimed |
| EP-2881395-A1 | PIPERAZINOTRIZOLE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF IN DRUG PREPARATION | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2015-06-10 | — | — | EP | claimed |
| CN-103570725-A | Piperazidinoltriazole compound as well as preparation method and application thereof | SHANGHAI INST MATERIA MEDICA | 2014-02-12 | — | — | CN | claimed |
| EP-4659658-A1 | SENSOR PROTECTIVE FILM AND METHOD OF PREPARATION AND USE | Shanghai United Imaging Microelectronics Technology Co., Ltd. (CN) | 2025-12-10 | — | — | EP | disclosed |
| CN-119775261-A | Collagen 1 translation inhibitors and methods of use thereof | 艾尼莫生物科技公司 | 2025-04-08 | — | — | CN | disclosed |
| CN-115427404-B | Collagen 1 translation inhibitors and methods of use thereof | 艾尼莫生物科技公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-118852137-A | Triazole piperazine compound and preparation method and application thereof | 山东大学深圳研究院 | 2024-10-29 | — | — | CN | disclosed |
| CN-1934112-A | Fused heterocyclic compounds and their use as metabotropic glutamate receptor antagonists | ASTRAZENECA AB (SE) | 2007-03-21 | — | — | CN | disclosed |
| US-6894054-B2 | Heterocyclic inhibitors of glycine transporter 2 | TELIK, INC. (US) | 2005-05-17 | — | — | US | disclosed |
| US-20030073726-A1 | Heterocyclic inhibitors of glycine transporter 2 | TELIK, INC. | 2003-04-17 | — | — | US | disclosed |
| EP-0397327-B1 | Process for dissolving tin and tin alloys | TOKAI ELECTRO CHEMICAL CO (JP) | 1996-07-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150166544-A1 | PIPERAZINOTRIAZOLE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF IN DRUG PREPARATION | PARP1, PARP11, PARP8 | BPTF 156/4885PLD1 2090/4885CASP1 23/4885 |
| US-20230203060-A1 | FUSED TRICYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | KRAS, NRAS, TP53 | BPTF 2324/4885PLD1 3609/4885CASP1 1606/4885 |
| US-20030073726-A1 | Heterocyclic inhibitors of glycine transporter 2 | SLC1A2, SLC1A1, SLC1A3 | BPTF 2624/4885PLD1 3550/4885CASP1 3160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.