SCHEMBL1013578

SCHEMBL1013578

CC1C(=O)N(CO)C(C)CN1C

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.34
BRD4 O60885 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11478542 0.69 L3MBTL1 (0.38) L3MBTL1
SCHEMBL313704 0.68 L3MBTL1 (0.41) L3MBTL1BRD4
SCHEMBL5487071 0.68 L3MBTL1 (0.41) L3MBTL1BRD4
SCHEMBL503016 0.65 L3MBTL1 (0.42) L3MBTL1
Dioxane SCHEMBL10501245 0.62 L3MBTL1 (0.35) L3MBTL1BRD4
SCHEMBL11288962 0.61
SCHEMBL1461449 0.61 L3MBTL1 (0.42) L3MBTL1
SCHEMBL5033987 0.60 L3MBTL1 (0.33) L3MBTL1
SCHEMBL12418938 0.60 L3MBTL1 (0.56) L3MBTL1
SCHEMBL11288959 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2271346-A2 MONOCYCLIC CGRP RECEPTOR ANTAGONISTS Merck Sharp & Dohme Corp. (US) 2011-01-12 EP disclosed
WO-2009120652-A2 MONOCYCLIC CGRP RECEPTOR ANTAGONISTS MERCK & CO., INC. (US) 2009-10-01 WO disclosed