Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 8/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | FABP7 | O15540 | 1/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16589450 | 0.89 | ALDH1A1 (0.49) | POLBFKBP1AALDH1A1HPGDFABP7 | |
| SCHEMBL24066813 | 0.86 | ALDH1A1 (0.44) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL13179991 | 0.85 | POLB (0.49) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL12604640 | 0.85 | POLB (0.49) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL8923967 | 0.85 | POLB (0.49) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL21716526 | 0.84 | POLB (0.45) | POLBFKBP1AALDH1A1HPGD | |
| SCHEMBL4662072 | 0.83 | MEN1 (0.50) | POLBALDH1A1 | |
| SCHEMBL5568192 | 0.83 | MEN1 (0.50) | POLBALDH1A1 | |
| SCHEMBL5568190 | 0.83 | MEN1 (0.50) | POLBALDH1A1 | |
| SCHEMBL8269795 | 0.83 | MEN1 (0.50) | POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE43298-E1 | Peptides as NS3-serine protease inhibitors of hepatitis C virus | SCHERING CORPORATION (US) | 2012-04-03 | — | — | US | disclosed |