Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.51 |
| ▸ | CA3 | P07451 | 2/20 | 0.50 |
| ▸ | CA5A | P35218 | 2/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3433785 | 0.92 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL10137981 | 0.86 | MEN1 (0.58) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL12393230 | 0.86 | EPHX1 (0.73) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL12453390 | 0.83 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL17367966 | 0.81 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL24173750 | 0.79 | MEN1 (0.49) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL20185561 | 0.78 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL14096591 | 0.76 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL12393215 | 0.76 | ALDH1A1 (0.75) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL27889238 | 0.75 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389745-B2 | Phosphonate fluorescent dyes and conjugates | ELITECH HOLDING B.V. (NL) | 2013-03-05 | — | — | US | disclosed |
| US-20120116079-A1 | PHOSPHONATE FLUORESCENT DYES AND CONJUGATES | ELITECHGROUP MDX LLC | 2012-05-10 | — | — | US | disclosed |