Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.45 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26768678 | 0.84 | BAZ2B (0.56) | ALDH1A1CYP3A4CYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL5521150 | 0.83 | MEN1 (0.51) | TDP1MAPK1ALDH1A1CYP3A4CYP11B1 | |
| SCHEMBL10138010 | 0.83 | CYP11B1 (0.47) | ALDH1A1CYP11B1CYP11B2SMN1; SMN2BAZ2B | |
| SCHEMBL27821291 | 0.83 | BAZ2B (0.53) | MAPK1ALDH1A1CYP3A4CYP11B1CYP11B2 | |
| SCHEMBL3781954 | 0.80 | CYP3A4 (0.42) | TDP1ALDH1A1CYP3A4KDM4ETAAR1 | |
| SCHEMBL3794745 | 0.79 | TDP1 (0.56) | TDP1MAPK1ALDH1A1CYP3A4CYP11B1 | |
| SCHEMBL7832063 | 0.78 | MEN1 (0.47) | TDP1MAPK1ALDH1A1CYP3A4CYP11B1 | |
| SCHEMBL7143439 | 0.77 | CYP3A4 (0.62) | TDP1MAPK1ALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL14457620 | 0.77 | TDP1 (0.54) | TDP1MAPK1ALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL10138011 | 0.77 | APP (0.51) | TDP1MAPK1ALDH1A1SMN1; SMN2BAZ2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389745-B2 | Phosphonate fluorescent dyes and conjugates | ELITECH HOLDING B.V. (NL) | 2013-03-05 | — | — | US | disclosed |
| US-20120116079-A1 | PHOSPHONATE FLUORESCENT DYES AND CONJUGATES | ELITECHGROUP MDX LLC | 2012-05-10 | — | — | US | disclosed |