Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5521150 | 0.94 | MEN1 (0.51) | MEN1KMT2ANPSR1ALOX12MAPT | |
| SCHEMBL5510993 | 0.94 | MEN1 (0.48) | MEN1KMT2ANPSR1ALOX12MAPT | |
| SCHEMBL14686282 | 0.84 | CA1 (0.47) | MEN1KMT2ANPSR1ALOX12MAPT | |
| SCHEMBL5250908 | 0.81 | CYP11B1 (0.50) | MEN1KMT2ANPSR1ALOX12MAPT | |
| SCHEMBL1131926 | 0.80 | MEN1 (0.47) | MEN1KMT2ANPSR1ALOX12MAPT | |
| SCHEMBL791494 | 0.80 | MEN1 (0.50) | MEN1KMT2ANPSR1ALOX12MAPT | |
| SCHEMBL27768579 | 0.80 | BACE1 (0.47) | KMT2ANPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL28792743 | 0.80 | PIN1 (0.46) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL26768678 | 0.79 | BAZ2B (0.56) | MEN1KMT2ANPSR1MAPTRAB9A | |
| SCHEMBL10138010 | 0.78 | CYP11B1 (0.47) | MEN1KMT2AMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1162196-A1 | FUSED-RING COMPOUNDS AND USE THEREOF AS DRUGS | JAPAN TOBACCO INC. (JP) | 2001-12-12 | — | — | EP | disclosed |