Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.51 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.46 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.46 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10139723 | 0.87 | KMT2A (0.47) | SIRT2SIRT1KMT2AMEN1RAB9A | |
| SCHEMBL20569799 | 0.84 | SIRT2 (0.47) | SIRT2SIRT1KMT2AMEN1GRIA1 | |
| SCHEMBL30349795 | 0.82 | CYP1A2 (0.60) | SIRT2SIRT1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9725457 | 0.82 | SIRT2 (0.51) | SIRT2SIRT1KMT2AMEN1GRIA1 | |
| Hydrochloric Acid SCHEMBL9725396 | 0.81 | SIRT2 (0.53) | SIRT2SIRT1KMT2AMEN1RAB9A | |
| SCHEMBL28414336 | 0.80 | SIRT2 (0.49) | SIRT2SIRT1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10169863 | 0.80 | KMT2A (0.55) | KMT2AMEN1RAB9AGAASMN1; SMN2 | |
| SCHEMBL29203245 | 0.80 | SIRT2 (0.48) | SIRT2SIRT1KMT2AMEN1GRIA1 | |
| SCHEMBL29203248 | 0.80 | SIRT2 (0.48) | SIRT2SIRT1KMT2AMEN1GRIA1 | |
| SCHEMBL30881349 | 0.80 | SIRT2 (0.48) | SIRT2SIRT1KMT2AMEN1GRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012059932-A1 | 2, 4 -DIAMINOPYRIMIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2012-05-10 | — | — | WO | disclosed |