Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.36 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | GPR183 | P32249 | 1/20 | 0.36 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL565835 | 0.84 | ALOX15 (0.54) | ALOX15HDAC6TNNC1S1PR1SGPL1 | |
| SCHEMBL566606 | 0.75 | ALOX15 (1.00) | ALOX15HDAC6TNNC1S1PR1SGPL1 | |
| Hydrochloric Acid SCHEMBL566330 | 0.74 | ALOX15 (0.98) | ALOX15HDAC6TNNC1S1PR1SGPL1 | |
| SCHEMBL17244022 | 0.71 | S1PR1 (0.37) | ALOX15TNNC1S1PR1SGPL1S1PR4 | |
| SCHEMBL3647482 | 0.68 | HDAC6 (0.45) | HDAC6CNR2EPHX2MAPK14TBXA2R | |
| SCHEMBL3650543 | 0.68 | HDAC6 (0.45) | HDAC6CNR2EPHX2MAPK14TBXA2R | |
| SCHEMBL3645557 | 0.68 | HDAC6 (0.45) | HDAC6CNR2EPHX2MAPK14TBXA2R | |
| SCHEMBL177179 | 0.67 | PTGDR (0.42) | ALOX15HDAC6TBXA2RALDH1A1 | |
| SCHEMBL29309827 | 0.62 | HDAC6 (0.76) | ALOX15HDAC6CNR2EPHX2S1PR1 | |
| SCHEMBL24105939 | 0.61 | EPHX2 (0.53) | HDAC6CNR2EPHX2S1PR1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9181182-B2 | S1P receptors modulators | AKAAL PHARMA PTY LTD (AU) | 2015-11-10 | — | — | US | disclosed |
| US-20120034270-A1 | S1P Receptors Modulators | AKAAL PHARMA PTY LTD (AU) | 2012-02-09 | — | — | US | disclosed |
| US-20120034270-A1 | S1P Receptors Modulators | AKAAL PHARMA PTY LTD (AU) | 2012-02-09 | — | — | US | disclosed |
| WO-2010042998-A1 | S1P RECEPTORS MODULATORS | AKAAL PHARMA PTY LTD (AU) | 2010-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120034270-A1 | S1P Receptors Modulators | S1PR1, S1PR5, S1PR3 | ALOX15 633/4885HDAC6 2352/4885CNR2 35/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.