Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 5/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.36 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.36 |
| ▸ | GPR183 | P32249 | 1/20 | 0.36 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.36 |
| ▸ | RARA | P10276 | 3/20 | 0.36 |
| ▸ | RARB | P10826 | 3/20 | 0.36 |
| ▸ | RARG | P13631 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL566087 | 0.99 | S1PR1 (0.39) | S1PR1ALOX15HDAC11S1PR3CYP3A4 | |
| SCHEMBL566953 | 0.86 | HDAC11 (0.33) | S1PR1HDAC11CYP3A4CYP2D6RARA | |
| SCHEMBL10139270 | 0.86 | RARA (0.45) | S1PR1ALOX15HDAC11S1PR3CYP3A4 | |
| SCHEMBL565403 | 0.83 | KDM4E (0.40) | S1PR1HDAC11CYP3A4RARARARB | |
| SCHEMBL566429 | 0.81 | S1PR1 (0.60) | S1PR1S1PR3CYP3A4CYP2C8CYP2D6 | |
| Hydrochloric Acid SCHEMBL567052 | 0.81 | S1PR1 (0.59) | S1PR1S1PR3CYP3A4CYP2C8CYP2D6 | |
| SCHEMBL2867798 | 0.80 | RARA (0.43) | S1PR1ALOX15HDAC11S1PR3CYP3A4 | |
| SCHEMBL10139271 | 0.80 | HDAC11 (0.53) | S1PR1ALOX15HDAC11S1PR3RARA | |
| Hydrochloric Acid SCHEMBL566401 | 0.79 | RARB (0.42) | S1PR1ALOX15HDAC11S1PR3CYP3A4 | |
| SCHEMBL566214 | 0.78 | POLB (0.43) | S1PR1ALOX15HDAC11RARARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9181182-B2 | S1P receptors modulators | AKAAL PHARMA PTY LTD (AU) | 2015-11-10 | — | — | US | disclosed |
| US-20120034270-A1 | S1P Receptors Modulators | AKAAL PHARMA PTY LTD (AU) | 2012-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120034270-A1 | S1P Receptors Modulators | S1PR1, S1PR5, S1PR3 | S1PR1 1/4885ALOX15 633/4885HDAC11 1612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.