Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | ACR | P10323 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22384820 | 0.94 | NR5A1 (0.59) | CYP1A2CYP19A1CYP2C9CYP2C19LTA4H | |
| SCHEMBL21919304 | 0.86 | CYP2C9 (0.50) | CYP1A2CYP19A1CYP2C9CYP2C19LTA4H | |
| SCHEMBL5532994 | 0.83 | NQO1 (0.64) | CYP1A2LTA4HTSHRCA12CA1 | |
| SCHEMBL4392335 | 0.83 | CYP2C9 (0.58) | CYP1A2CYP19A1CYP2C9CYP2C19LTA4H | |
| SCHEMBL28964341 | 0.83 | CYP2C9 (0.58) | CYP1A2CYP19A1CYP2C9CYP2C19LTA4H | |
| SCHEMBL28964340 | 0.83 | CYP2C9 (0.58) | CYP1A2CYP19A1CYP2C9CYP2C19LTA4H | |
| SCHEMBL26850 | 0.82 | LTA4H (0.70) | CYP1A2CYP19A1CYP2C9CYP2C19LTA4H | |
| SCHEMBL20776786 | 0.82 | FURIN (0.48) | CYP1A2CYP19A1CYP2C9CYP2C19GAA | |
| SCHEMBL31644346 | 0.79 | CYP2C9 (0.54) | CYP1A2CYP19A1CYP2C9CYP2C19LTA4H | |
| SCHEMBL414168 | 0.79 | CYP1A2 (0.50) | CYP1A2CYP19A1CYP2C9CYP2C19LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132724-A1 | AZO(HETERO)ARYL DERIVATIVES FOR USE AS RADIOSWITCHS AND THEIR USE IN THERAPY | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2025-06-26 | — | — | WO | disclosed |
| US-20180066007-A1 | Macrocyclic Compounds And Methods Of Making And Using The Same | BioVersys AG (CH) | 2018-03-08 | — | — | US | disclosed |
| WO-2012059932-A1 | 2, 4 -DIAMINOPYRIMIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2012-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180066007-A1 | Macrocyclic Compounds And Methods Of Making And Using The Same | CCNO, PTGDR, CCNE1 | CYP1A2 1041/4885CYP19A1 1310/4885CYP2C9 729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.