SCHEMBL1014043

SCHEMBL1014043

COc1cc(OC)nc(NC(=O)NS(=O)(=O)c2ncccc2C(=O)N(OC)OC)n1

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.54
CDK1 P06493 1/20 0.48
MAPT P10636 2/20 0.43
TP53 P04637 1/20 0.43
GLA P06280 1/20 0.43
CYP1A2 P05177 1/20 0.40
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.37
USP2 O75604 1/20 0.37
RXFP1 Q9HBX9 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nicosulfuron SCHEMBL8536419 0.91 CDK1 (0.59) GAACDK1MAPTTP53GLA
Nicosulfuron SCHEMBL29440408 0.91 CDK1 (0.59) GAACDK1MAPTTP53GLA
Nicosulfuron SCHEMBL22938 0.91 CDK1 (0.59) GAACDK1MAPTTP53GLA
Nicosulfuron SCHEMBL15524973 0.90 CDK1 (0.58) GAACDK1MAPTTP53GLA
Nicosulfuron SCHEMBL27956627 0.90 CDK1 (0.58) GAACDK1MAPTTP53GLA
Nicosulfuron SCHEMBL28975699 0.90 CDK1 (0.58) GAACDK1MAPTTP53GLA
Nicosulfuron SCHEMBL28260534 0.90 CDK1 (0.58) GAACDK1MAPTTP53GLA
SCHEMBL20534922 0.89 GAA (0.51) GAACDK1MAPTTP53GLA
Nicosulfuron SCHEMBL27919803 0.88 CDK1 (0.56) GAACDK1MAPTTP53GLA
SCHEMBL9628294 0.87 GAA (0.56) GAACDK1MAPTTP53GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0965265-B1 AHAS-inhibiting herbicide resistant wheat and method for selection thereof BASF SE (DE) 2011-01-05 EP disclosed
US-7034208-B1 Ahas inhibiting herbicide resistant wheat and method for selection thereof BASF AKTIENGELLSCHAFT (DE) 2006-04-25 US disclosed
US-6339184-B1 SCREENING FOR THE SELECTION OF MUTATIONS WHICH CONFER ACETOHYDROXYACID SYNTHASE RESISTANCE TO WHEAT BASF AKTIENGELLSCHAFT (DE) 2002-01-15 US disclosed
EP-0508161-B1 Use of AHAS inhibiting herbicide resistant wheat and method for selection thereof AMERICAN CYANAMID CO (US) 2000-05-10 EP disclosed
EP-0965265-A2 AHAS-inhibiting herbicide resistant wheat and method for selection thereof AMERICAN CYANAMID COMPANY (US) 1999-12-22 EP disclosed
EP-0508161-A1 AHAS inhibiting herbicide resistant wheat and method for selection thereof AMERICAN CYANAMID COMPANY (US) 1992-10-14 EP disclosed