SCHEMBL9628294

SCHEMBL9628294

COC(=O)c1cccnc1S(=O)(=O)NC(=O)Nc1nc(OC)cc(OC)n1

nearest known ligand 0.62

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.56
CDK1 P06493 1/20 0.47
MAPT P10636 2/20 0.43
TP53 P04637 1/20 0.43
GLA P06280 1/20 0.43
CYP1A2 P05177 1/20 0.43
KMT2A Q03164 2/20 0.41
SLC40A1 Q9NP59 1/20 0.40
MEN1 O00255 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9040212 0.91 GAA (0.56) GAACDK1MAPTTP53GLA
SCHEMBL10365723 0.91 GAA (0.56) GAACDK1MAPTTP53GLA
SCHEMBL9359642 0.90 GAA (0.55) GAACDK1MAPTTP53GLA
SCHEMBL9363855 0.89 GAA (0.54) GAACDK1MAPTTP53GLA
SCHEMBL10365711 0.88 GAA (0.53) GAACDK1MAPTTP53GLA
Nicosulfuron SCHEMBL22938 0.88 CDK1 (0.59) GAACDK1MAPTTP53GLA
Nicosulfuron SCHEMBL8536419 0.88 CDK1 (0.59) GAACDK1MAPTTP53GLA
Nicosulfuron SCHEMBL29440408 0.88 CDK1 (0.59) GAACDK1MAPTTP53GLA
SCHEMBL1014043 0.87 GAA (0.54) GAACDK1MAPTTP53GLA
Nicosulfuron SCHEMBL15524973 0.87 CDK1 (0.58) GAACDK1MAPTTP53GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5084086-A Triazinyl or pyrimidinyl sulfonylureas as herbicides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-01-28 US disclosed
US-5084082-A Plant mutants with resistance to sulfonylurea derivative herbi cides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-01-28 US disclosed