Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 9/20 | 0.49 |
| ▸ | CA2 | P00918 | 9/20 | 0.49 |
| ▸ | CA12 | O43570 | 5/20 | 0.49 |
| ▸ | CA9 | Q16790 | 5/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL902008 | 1.00 | MEN1 (0.59) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL6837317 | 0.98 | TDP1 (0.61) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL6517345 | 0.95 | MEN1 (0.66) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL902132 | 0.95 | MEN1 (0.66) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL30299126 | 0.89 | TDP1 (0.50) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL13055386 | 0.88 | MEN1 (0.56) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL12341542 | 0.85 | MEN1 (0.65) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL24884098 | 0.84 | CA1 (0.58) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL21449024 | 0.84 | CA1 (0.58) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL25354053 | 0.84 | MAOA (0.46) | MEN1KMT2AGAATDP1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012055031-A1 | HIV PROTEASE INHIBITORS | MERCK CANADA INC. (CA) | 2012-05-03 | — | — | WO | disclosed |