Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.41 |
| ▸ | F9 | P00740 | 3/20 | 0.41 |
| ▸ | F11 | P03951 | 3/20 | 0.41 |
| ▸ | F2 | P00734 | 6/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.37 |
| ▸ | F7 | P08709 | 3/20 | 0.36 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 4/20 | 0.36 |
| ▸ | PLAU | P00749 | 4/20 | 0.36 |
| ▸ | PLAT | P00750 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10140058 | 0.93 | F10 (0.49) | F10F9F11F2PRSS1 | |
| SCHEMBL10173105 | 0.84 | HTR1A (0.41) | F10TNIK | |
| SCHEMBL10140918 | 0.84 | F10 (0.37) | F10PRSS1TNIK | |
| SCHEMBL10140047 | 0.82 | F10 (0.40) | F10PRSS1TNIK | |
| SCHEMBL7982567 | 0.82 | F10 (0.58) | F10F9F11F2PRSS1 | |
| SCHEMBL7966289 | 0.82 | F10 (0.39) | F10PRSS1TNIK | |
| SCHEMBL10140061 | 0.81 | F10 (0.48) | F10F9F11F2PRSS1 | |
| SCHEMBL10140114 | 0.81 | F10 (0.47) | F10F9F11F2PRSS1 | |
| SCHEMBL10140728 | 0.81 | F10 (0.53) | F10F9F11F2PRSS1 | |
| SCHEMBL10139884 | 0.81 | F10 (0.48) | F10F9F11F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148363-B2 | Heterocyclic compounds as factor IXA inhibitors | SCHERING CORPORATION (US) | 2012-04-03 | — | — | US | disclosed |
| US-8148363-B2 | Heterocyclic compounds as factor IXA inhibitors | SCHERING CORPORATION (US) | 2012-04-03 | — | — | US | disclosed |