Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CCR1 | P32246 | 3/20 | 0.44 |
| ▸ | CCR5 | P51681 | 3/20 | 0.44 |
| ▸ | CCR8 | P51685 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ALPL | P05186 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | ALPG | P10696 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17907394 | 0.87 | KDM4E (0.39) | KDM4EALOX15L3MBTL1TP53SMN1; SMN2 | |
| SCHEMBL30604624 | 0.81 | KDM4E (0.34) | KDM4ETP53 | |
| Hydrochloric Acid SCHEMBL18670804 | 0.81 | KDM4E (0.34) | KDM4ETP53 | |
| SCHEMBL28999623 | 0.77 | KDM4E (0.32) | KDM4ETP53 | |
| SCHEMBL503234 | 0.77 | KDM4E (0.61) | KDM4EALOX15L3MBTL1TP53SMN1; SMN2 | |
| SCHEMBL28999633 | 0.76 | KDM4E (0.32) | KDM4ETP53 | |
| SCHEMBL5612663 | 0.74 | CCR1 (0.61) | KDM4ECCR1CCR8ALDH1A1 | |
| SCHEMBL28352665 | 0.73 | KDM4E (0.55) | KDM4EALOX15L3MBTL1TP53SMN1; SMN2 | |
| SCHEMBL6164001 | 0.71 | BTK (0.51) | KDM4ECCR1CCR8 | |
| Pyridine SCHEMBL27602451 | 0.71 | KDM4E (0.53) | KDM4EALOX15L3MBTL1TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012052412-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2012-04-26 | — | — | WO | disclosed |