SCHEMBL17907394

SCHEMBL17907394

c1cc(-c2c[nH]nn2)nc(-c2c[nH]nn2)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.39
L3MBTL1 Q9Y468 3/20 0.39
CCR1 P32246 2/20 0.39
CCR8 P51685 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
LMNA P02545 2/20 0.39
TP53 P04637 2/20 0.39
ALOX15 P16050 2/20 0.39
HTT P42858 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
ALPL P05186 1/20 0.39
HSP90AA1 P07900 1/20 0.39
ALPI P09923 1/20 0.39
ALPG P10696 1/20 0.39
MAPK1 P28482 1/20 0.39
CCR5 P51681 1/20 0.39
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
RAB9A P51151 2/20 0.37
ALDH1A1 P00352 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10142595 0.87 KDM4E (0.44) KDM4EL3MBTL1CCR1CCR8TDP1
SCHEMBL5612663 0.86 CCR1 (0.61) KDM4ECCR1CCR8ALDH1A1METAP2
SCHEMBL6164001 0.82 BTK (0.51) KDM4ECCR1CCR8BTK
SCHEMBL87533 0.82
SCHEMBL31345402 0.78 ECE1 (0.38) KDM4ETDP1LMNAALOX15ALDH1A1
SCHEMBL503234 0.76 KDM4E (0.61) KDM4EL3MBTL1CCR1CCR8TDP1
SCHEMBL13931019 0.76 KDM4E (0.35) KDM4EL3MBTL1LMNATP53ALOX15
SCHEMBL9730610 0.76 RAB9A (0.46) KDM4ETDP1LMNATP53ALOX15
SCHEMBL1646236 0.74 GP6 (0.37) MEN1KMT2ARAB9AALDH1A1METAP2
SCHEMBL28266911 0.74 RAB9A (0.45) KDM4ETDP1LMNATP53ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3042645-B2 Dental composites with improved storage stability IVOCLAR VIVADENT AG (LI) 2025-03-12 EP claimed
US-12162899-B2 Photochromic germole-fused diarylethenes and production thereof THE UNIVERSITY OF HONG KONG (CN) 2024-12-10 US claimed
CN-116425791-A Photochromic germanium-doped cyclopentadiene condensed diaryl ethylene and preparation thereof 香港大学 2023-07-14 CN claimed
US-20230167139-A1 PHOTOCHROMIC GERMOLE-FUSED DIARYLETHENES AND PRODUCTION THEREOF THE UNIVERSITY OF HONG KONG (CN) 2023-06-01 US claimed
US-11357708-B2 Dental composites with improved storage stability IVOCLAR VIVADENT AG (LI) 2022-06-14 US claimed
EP-3042645-B1 Dental composites with improved storage stability IVOCLAR VIVADENT AG (LI) 2022-04-27 EP claimed
CN-107308993-B The preparation of the support type porous organic polymer catalyst of hydrogen is produced for Catalyzed by Formic Acid 福建师范大学 2019-10-18 CN claimed
US-20180318178-A1 DENTAL COMPOSITES WITH IMPROVED STORAGE STABILITY IVOCLAR VIVADENT AG (LI) 2018-11-08 US claimed
EP-3042645-A1 Dental composites with improved storage stability Ivoclar Vivadent AG (LI) 2016-07-13 EP claimed
EP-3042645-B2 Dental composites with improved storage stability IVOCLAR VIVADENT AG (LI) 2025-03-12 EP disclosed
US-12162899-B2 Photochromic germole-fused diarylethenes and production thereof THE UNIVERSITY OF HONG KONG (CN) 2024-12-10 US disclosed
US-20230365754-A1 CROSS-LINKABLE ALLYLAMIDO POLYMERS UNIVERSITEIT GENT (BE) 2023-11-16 US disclosed
EP-4229115-A1 CROSS-LINKABLE ALLYLAMIDO POLYMERS Universiteit Gent (BE) 2023-08-23 EP disclosed
CN-116425791-A Photochromic germanium-doped cyclopentadiene condensed diaryl ethylene and preparation thereof 香港大学 2023-07-14 CN disclosed
CN-107308993-B The preparation of the support type porous organic polymer catalyst of hydrogen is produced for Catalyzed by Formic Acid 福建师范大学 2019-10-18 CN disclosed
CN-109908873-A A kind of material and preparation method of the adsorption uranium from alkaline nuclear waste 兰州大学 2019-06-21 CN disclosed
US-20180318178-A1 DENTAL COMPOSITES WITH IMPROVED STORAGE STABILITY IVOCLAR VIVADENT AG (LI) 2018-11-08 US disclosed
CN-107308993-A The preparation of the support type porous organic polymer catalyst of hydrogen is produced for Catalyzed by Formic Acid 福建师范大学 2017-11-03 CN disclosed
EP-3042645-A1 Dental composites with improved storage stability Ivoclar Vivadent AG (LI) 2016-07-13 EP disclosed
CN-1730509-A Ag coordinated polymer and preparation method and uses UNIV NANKAI (CN) 2006-02-08 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12162899-B2 Photochromic germole-fused diarylethenes and production thereof AGL, GMNN, GAK KDM4E 2397/4885L3MBTL1 2882/4885CCR1 3987/4885
US-20230167139-A1 PHOTOCHROMIC GERMOLE-FUSED DIARYLETHENES AND PRODUCTION THEREOF AGL, GMNN, GAK KDM4E 2397/4885L3MBTL1 2882/4885CCR1 3987/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.