Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | CCKBR | P32239 | 5/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
| ▸ | CCKAR | P32238 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10144437 | 0.93 | HDAC1 (0.40) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL10144455 | 0.84 | CCKBR (0.40) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL10144456 | 0.82 | CCKBR (0.41) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL10143368 | 0.78 | HDAC3 (0.44) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL10143385 | 0.69 | MDM2 (0.38) | HDAC1HDAC4SIRT5CA1CA2 | |
| SCHEMBL10144413 | 0.69 | CA1 (0.40) | HDAC1HDAC4SIRT5CA1CA2 | |
| SCHEMBL10143383 | 0.69 | TLR2 (0.40) | SIRT5CA1CA2 | |
| SCHEMBL10144194 | 0.68 | MDM2 (0.39) | HDAC1HDAC4SIRT5CA1CA2 | |
| SCHEMBL30561254 | 0.67 | MEN1 (0.61) | — | |
| SCHEMBL22038251 | 0.67 | MEN1 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |