Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR2 | O43603 | 13/20 | 0.70 |
| ▸ | GALR1 | P47211 | 4/20 | 0.65 |
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CCND3 | P30281 | 2/20 | 0.46 |
| ▸ | CCNK | O75909 | 1/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | CCND1 | P24385 | 1/20 | 0.44 |
| ▸ | CCND2 | P30279 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10143476 | 0.97 | GALR2 (0.71) | GALR2GALR1AURKAMAPTCCND3 | |
| SCHEMBL10143663 | 0.87 | GALR2 (0.51) | GALR2GALR1MAPTCCND3CCNK | |
| SCHEMBL10143391 | 0.83 | GALR2 (1.00) | GALR2GALR1AURKA | |
| SCHEMBL10143741 | 0.82 | GALR2 (0.79) | GALR2GALR1AURKA | |
| SCHEMBL10143662 | 0.81 | GALR2 (0.82) | GALR2GALR1AURKA | |
| SCHEMBL10143469 | 0.81 | GALR2 (0.82) | GALR2GALR1AURKA | |
| SCHEMBL10143436 | 0.81 | GALR2 (0.64) | GALR2GALR1AURKAMAPTCCND3 | |
| SCHEMBL10143487 | 0.81 | GALR2 (0.82) | GALR2GALR1AURKA | |
| SCHEMBL10143620 | 0.81 | GALR2 (0.78) | GALR2GALR1AURKA | |
| SCHEMBL10143455 | 0.81 | GALR2 (0.80) | GALR2GALR1AURKAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |