Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR2 | O43603 | 5/20 | 0.64 |
| ▸ | GALR1 | P47211 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | CCND3 | P30281 | 2/20 | 0.47 |
| ▸ | CCNK | O75909 | 1/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | CDK9 | P50750 | 1/20 | 0.47 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CDK4 | P11802 | 1/20 | 0.46 |
| ▸ | CCND1 | P24385 | 1/20 | 0.46 |
| ▸ | CCND2 | P30279 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 2/20 | 0.45 |
| ▸ | JAK3 | P52333 | 2/20 | 0.45 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10143767 | 0.83 | MAPT (0.67) | GALR2GALR1ALDH1A1MAPTCCND3 | |
| SCHEMBL10143471 | 0.81 | GALR2 (0.70) | GALR2GALR1ALDH1A1MAPTCCND3 | |
| SCHEMBL17310093 | 0.81 | SUV39H2 (0.49) | GALR2GALR1ALDH1A1MAPTSLC2A1 | |
| SCHEMBL10143551 | 0.80 | GALR2 (0.67) | GALR2GALR1ALDH1A1MAPTSLC2A1 | |
| SCHEMBL10143394 | 0.80 | GALR2 (0.67) | GALR2GALR1ALDH1A1MAPTSLC2A1 | |
| SCHEMBL18153409 | 0.80 | GALR2 (0.54) | GALR2GALR1MAPTCCND3CCNK | |
| SCHEMBL10144326 | 0.79 | GALR2 (1.00) | GALR2GALR1 | |
| SCHEMBL10143476 | 0.79 | GALR2 (0.71) | GALR2GALR1ALDH1A1MAPTCCND3 | |
| SCHEMBL21796892 | 0.79 | SUV39H2 (0.49) | GALR2GALR1ALDH1A1MAPTLMNA | |
| SCHEMBL10143742 | 0.78 | JAK2 (0.53) | GALR2GALR1MAPTSLC2A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |