Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 3/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10144445 | 0.93 | TLR2 (0.46) | TLR2PTPN1DPP8MDM2 | |
| SCHEMBL10144408 | 0.91 | TLR2 (0.47) | TLR2PTPN1 | |
| SCHEMBL10144449 | 0.91 | TLR2 (0.44) | TLR2PTPN1DPP8MDM2 | |
| SCHEMBL10143408 | 0.90 | MDM2 (0.41) | TLR2MDM2 | |
| SCHEMBL10144450 | 0.89 | TLR2 (0.43) | TLR2PTPN1DPP8MDM2 | |
| SCHEMBL10143416 | 0.87 | TLR2 (0.41) | TLR2PTPN1MDM2 | |
| SCHEMBL10143401 | 0.85 | TLR2 (0.46) | TLR2PTPN1DPP8MMP3HDAC1 | |
| SCHEMBL10144109 | 0.83 | MDM2 (0.42) | TLR2MDM2 | |
| SCHEMBL10143538 | 0.82 | TLR2 (0.54) | TLR2PTPN1MMP3HDAC1HDAC2 | |
| SCHEMBL10143586 | 0.82 | MDM2 (0.42) | MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |