Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 3/20 | 0.45 |
| ▸ | GABRP | O00591 | 5/20 | 0.45 |
| ▸ | GABRD | O14764 | 5/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.45 |
| ▸ | GABRE | P78334 | 5/20 | 0.45 |
| ▸ | GABRA6 | Q16445 | 5/20 | 0.45 |
| ▸ | GABRG1 | Q8N1C3 | 5/20 | 0.45 |
| ▸ | GABRG3 | Q99928 | 5/20 | 0.45 |
| ▸ | GABRQ | Q9UN88 | 5/20 | 0.45 |
| ▸ | TNKS | O95271 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30615552 | 1.00 | MEN1 (0.47) | MEN1KMT2AAURKAGABRPGABRD | |
| SCHEMBL30615480 | 0.87 | GABRP (0.45) | MEN1KMT2AAURKAGABRPGABRD | |
| SCHEMBL21463390 | 0.86 | TNKS (0.41) | MEN1KMT2AAURKAGABRPGABRD | |
| SCHEMBL30615431 | 0.86 | TNKS (0.41) | MEN1KMT2AAURKAGABRPGABRD | |
| SCHEMBL30615427 | 0.83 | AURKA (0.47) | MEN1KMT2AAURKAGABRPGABRD | |
| SCHEMBL21463426 | 0.82 | TNKS (0.40) | MEN1KMT2AAURKAGABRPGABRD | |
| SCHEMBL21464133 | 0.82 | AURKA (0.49) | MEN1KMT2AAURKAGABRPGABRD | |
| SCHEMBL21464135 | 0.82 | AURKA (0.48) | MEN1KMT2AAURKAGABRPGABRD | |
| SCHEMBL30615658 | 0.82 | AURKA (0.49) | MEN1KMT2AAURKAGABRPGABRD | |
| SCHEMBL30615432 | 0.82 | AURKA (0.48) | MEN1KMT2AAURKAGABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |