Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR2 | O43603 | 6/20 | 0.73 |
| ▸ | MAPT | P10636 | 8/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | GBA1 | P04062 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | GALR1 | P47211 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10143600 | 0.92 | GALR2 (0.63) | GALR2MAPTMAPK1TDP1GBA1 | |
| SCHEMBL10143494 | 0.90 | MAPT (0.61) | GALR2MAPTMAPK1TDP1GBA1 | |
| SCHEMBL10143492 | 0.89 | GALR2 (0.59) | GALR2MAPTMAPK1TDP1GBA1 | |
| SCHEMBL10143650 | 0.89 | CTSL (0.61) | GALR2MAPTMAPK1TDP1GBA1 | |
| SCHEMBL10143739 | 0.89 | GALR2 (0.58) | GALR2MAPTMAPK1TDP1GBA1 | |
| SCHEMBL10143595 | 0.89 | GALR2 (0.58) | GALR2MAPTMAPK1TDP1GBA1 | |
| SCHEMBL10143641 | 0.88 | MAPT (0.59) | GALR2MAPTMAPK1TDP1GBA1 | |
| SCHEMBL10143391 | 0.84 | GALR2 (1.00) | GALR2GALR1 | |
| SCHEMBL14503015 | 0.83 | MEN1 (0.75) | GALR2MAPTMAPK1TDP1GBA1 | |
| SCHEMBL10143490 | 0.83 | GALR2 (0.52) | GALR2MAPTMAPK1TDP1GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |