Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 1.00 |
| ▸ | MAPT | P10636 | 11/20 | 1.00 |
| ▸ | NPC1 | O15118 | 11/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 10/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 1.00 |
| ▸ | MEN1 | O00255 | 7/20 | 1.00 |
| ▸ | HTT | P42858 | 6/20 | 0.66 |
| ▸ | TP53 | P04637 | 2/20 | 0.66 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.66 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.66 |
| ▸ | RELA | Q04206 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 6/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | XBP1 | P17861 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29033679 | 0.88 | KMT2A (0.78) | RAB9AMAPTNPC1KMT2ASMN1; SMN2 | |
| SCHEMBL17190844 | 0.88 | KMT2A (0.78) | RAB9AMAPTNPC1KMT2ASMN1; SMN2 | |
| SCHEMBL19535031 | 0.79 | KMT2A (0.64) | RAB9AMAPTNPC1KMT2ASMN1; SMN2 | |
| SCHEMBL19535032 | 0.79 | KMT2A (0.64) | RAB9AMAPTNPC1KMT2ASMN1; SMN2 | |
| SCHEMBL19321533 | 0.78 | MAPT (0.64) | RAB9AMAPTNPC1KMT2ASMN1; SMN2 | |
| SCHEMBL4929465 | 0.78 | PAX8 (0.73) | RAB9AMAPTNPC1KMT2ASMN1; SMN2 | |
| SCHEMBL10144051 | 0.75 | MAPT (1.00) | RAB9AMAPTNPC1KMT2ASMN1; SMN2 | |
| SCHEMBL1164645 | 0.73 | PAX8 (1.00) | RAB9AMAPTNPC1KMT2ASMN1; SMN2 | |
| SCHEMBL1164644 | 0.73 | PAX8 (1.00) | RAB9AMAPTNPC1KMT2ASMN1; SMN2 | |
| SCHEMBL29692738 | 0.73 | PAX8 (1.00) | RAB9AMAPTNPC1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | BIOMARIN PHARMACEUTICAL INC. | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | ENGASE, GALNT1, GALNT13 | RAB9A 3256/4885MAPT 2982/4885NPC1 764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.