Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 1.00 |
| ▸ | TSHR | P16473 | 4/20 | 1.00 |
| ▸ | HTT | P42858 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | USP2 | O75604 | 1/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19911304 | 0.78 | TSHR (0.71) | LMNATSHRHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL8599875 | 0.75 | POLB (0.65) | LMNATSHRHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL19911308 | 0.73 | LMNA (0.60) | LMNATSHRHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL12793331 | 0.72 | SMN1; SMN2 (0.71) | LMNATSHRHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL19848363 | 0.71 | GAA (0.68) | LMNATSHRHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL11607293 | 0.70 | HTT (0.70) | LMNATSHRHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL15071602 | 0.69 | TSHR (0.70) | LMNATSHRHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL15579278 | 0.68 | KCNH2 (0.64) | LMNATSHRHTTSMN1; SMN2KMT2A | |
| SCHEMBL8305327 | 0.68 | LMNA (0.91) | LMNATSHRALDH1A1SMN1; SMN2GAA | |
| SCHEMBL9914234 | 0.68 | TSHR (0.63) | LMNATSHRHTTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | BIOMARIN PHARMACEUTICAL INC. | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | ENGASE, GALNT1, GALNT13 | LMNA 4109/4885TSHR 2802/4885HTT 3785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.