Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.50 |
| ▸ | SRC | P12931 | 2/20 | 0.49 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6097652 | 0.82 | CYP1A2 (0.50) | MAPTALDH1A1MAP3K14SRCP2RX7 | |
| SCHEMBL31500060 | 0.81 | SMN1; SMN2 (0.69) | MAPTALDH1A1KDM4ENPSR1SMN1; SMN2 | |
| SCHEMBL19754188 | 0.77 | ALDH1A1 (0.47) | MAPTALDH1A1KDM4ENPSR1SMN1; SMN2 | |
| SCHEMBL19754181 | 0.77 | ALDH1A1 (0.47) | MAPTALDH1A1KDM4ENPSR1SMN1; SMN2 | |
| SCHEMBL19992650 | 0.75 | MAP3K14 (0.50) | MAPTALDH1A1MAP3K14 | |
| SCHEMBL28299678 | 0.74 | CYP1A2 (0.49) | MAPTALDH1A1KDM4ENPSR1MAP3K14 | |
| SCHEMBL19754187 | 0.73 | KDM4E (0.63) | MAPTALDH1A1KDM4ENPSR1SMN1; SMN2 | |
| SCHEMBL19754179 | 0.72 | KDM4E (0.51) | MAPTALDH1A1KDM4ENPSR1SMN1; SMN2 | |
| SCHEMBL19754108 | 0.72 | GRM4 (0.48) | MAPTALDH1A1KDM4ENPSR1SMN1; SMN2 | |
| SCHEMBL28301087 | 0.72 | SMN1; SMN2 (0.58) | MAPTALDH1A1KDM4ESRCSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | BIOMARIN PHARMACEUTICAL INC. | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | ENGASE, GALNT1, GALNT13 | MAPT 2982/4885ALDH1A1 2125/4885KDM4E 3708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.