Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 4/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.36 |
| ▸ | MEF2D | Q14814 | 3/20 | 0.36 |
| ▸ | REN | P00797 | 2/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10143501 | 0.91 | TLR2 (0.41) | TLR2MDM2HDAC4MEF2DEP300 | |
| SCHEMBL10144186 | 0.91 | TLR2 (0.44) | TLR2MDM2HDAC4MEF2DEP300 | |
| SCHEMBL10143521 | 0.91 | TLR2 (0.43) | TLR2MDM2HDAC4MEF2DEP300 | |
| SCHEMBL10143779 | 0.90 | TLR2 (0.45) | TLR2MDM2HDAC4MEF2DREN | |
| SCHEMBL10144161 | 0.89 | TLR2 (0.41) | TLR2MDM2HDAC4MEF2DEP300 | |
| SCHEMBL10143416 | 0.89 | TLR2 (0.41) | TLR2MDM2HDAC4MEF2DEP300 | |
| SCHEMBL10144113 | 0.87 | MDM2 (0.41) | TLR2MDM2 | |
| SCHEMBL10143778 | 0.87 | MDM2 (0.41) | TLR2MDM2HDAC4 | |
| SCHEMBL10144195 | 0.86 | TLR2 (0.44) | TLR2MDM2HDAC4MEF2DEP300 | |
| SCHEMBL10143403 | 0.86 | TLR2 (0.42) | TLR2MDM2HDAC4MEF2DEP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |