Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 4/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.37 |
| ▸ | MEF2D | Q14814 | 3/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10144186 | 0.93 | TLR2 (0.44) | TLR2HDAC4MEF2DEP300CPB2 | |
| SCHEMBL10143521 | 0.92 | TLR2 (0.43) | TLR2HDAC4MEF2DEP300CPB2 | |
| SCHEMBL10143779 | 0.92 | TLR2 (0.45) | TLR2HDAC4MEF2DEP300CPB2 | |
| SCHEMBL10143501 | 0.91 | TLR2 (0.41) | TLR2HDAC4MEF2DEP300CPB2 | |
| SCHEMBL10143416 | 0.91 | TLR2 (0.41) | TLR2HDAC4MEF2DEP300CPB2 | |
| SCHEMBL10143766 | 0.90 | MDM2 (0.40) | TLR2HDAC4CTSSCTSKMDM2 | |
| SCHEMBL10144112 | 0.89 | TLR2 (0.40) | TLR2HDAC4MEF2DEP300CPB2 | |
| SCHEMBL10144195 | 0.88 | TLR2 (0.44) | TLR2HDAC4MEF2DEP300CPB2 | |
| SCHEMBL10143403 | 0.88 | TLR2 (0.42) | TLR2HDAC4MEF2DEP300CPB2 | |
| Galnon SCHEMBL4464884 | 0.85 | TLR2 (0.44) | TLR2HDAC4MEF2DEP300CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |