Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | NPC1 | O15118 | 9/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.61 |
| ▸ | RAB9A | P51151 | 7/20 | 0.61 |
| ▸ | MEN1 | O00255 | 6/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
| ▸ | AHR | P35869 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5993312 | 0.85 | MAPT (0.67) | MAPTALDH1A1NPC1L3MBTL1KMT2A | |
| SCHEMBL14096082 | 0.82 | MAPT (0.73) | MAPTALDH1A1NPC1L3MBTL1KMT2A | |
| SCHEMBL13956754 | 0.81 | MAPT (0.69) | MAPTALDH1A1NPC1L3MBTL1KMT2A | |
| SCHEMBL14096079 | 0.80 | MAPT (0.78) | MAPTALDH1A1NPC1L3MBTL1KMT2A | |
| SCHEMBL14096111 | 0.79 | NPC1 (0.64) | MAPTALDH1A1NPC1L3MBTL1KMT2A | |
| SCHEMBL14096080 | 0.79 | MAPT (0.76) | MAPTALDH1A1NPC1L3MBTL1KMT2A | |
| SCHEMBL13956757 | 0.79 | NPC1 (0.66) | MAPTALDH1A1NPC1L3MBTL1KMT2A | |
| SCHEMBL14096110 | 0.79 | MAPT (0.61) | MAPTALDH1A1NPC1L3MBTL1KMT2A | |
| SCHEMBL2866259 | 0.78 | ALDH1A1 (0.61) | MAPTALDH1A1NPC1L3MBTL1KMT2A | |
| SCHEMBL13956746 | 0.78 | MAPT (0.74) | MAPTALDH1A1NPC1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | BIOMARIN PHARMACEUTICAL INC. | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | ENGASE, GALNT1, GALNT13 | MAPT 2982/4885ALDH1A1 2125/4885NPC1 764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.