Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR2 | O43603 | 14/20 | 0.75 |
| ▸ | GALR1 | P47211 | 6/20 | 0.51 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.45 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10144338 | 0.86 | GALR2 (1.00) | GALR2GALR1 | |
| SCHEMBL10143578 | 0.83 | GALR2 (0.73) | GALR2GALR1 | |
| SCHEMBL10143569 | 0.83 | GALR2 (0.73) | GALR2GALR1 | |
| SCHEMBL10143553 | 0.77 | GALR2 (0.48) | GALR2GALR1 | |
| SCHEMBL10143781 | 0.75 | GALR2 (0.80) | GALR2GALR1 | |
| SCHEMBL12485483 | 0.72 | MAPT (0.50) | GALR2 | |
| SCHEMBL10143561 | 0.72 | GALR2 (0.80) | GALR2GALR1 | |
| SCHEMBL10144352 | 0.70 | GALR2 (1.00) | GALR2GALR1 | |
| SCHEMBL10144179 | 0.68 | GALR2 (0.98) | GALR2GALR1 | |
| SCHEMBL10143556 | 0.68 | GALR2 (0.80) | GALR2GALR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |