Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 3/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13950759 | 0.84 | MAPT (0.54) | MAPTSMN1; SMN2GAAPOLBPPARG | |
| SCHEMBL13927337 | 0.83 | PPARA (0.45) | MAPTSMN1; SMN2GAAPOLBCDK2 | |
| SCHEMBL15080565 | 0.82 | CYP1A2 (0.61) | MAPTSMN1; SMN2PDGFRBPDGFRAMEN1 | |
| SCHEMBL13950754 | 0.81 | MAPT (0.50) | MAPTSMN1; SMN2GAAPOLBMEN1 | |
| SCHEMBL4500238 | 0.80 | MAPT (0.55) | MAPTSMN1; SMN2GAAPOLBPPARA | |
| SCHEMBL13950753 | 0.79 | NPC1 (0.48) | MAPTSMN1; SMN2GAAPOLBPPARA | |
| SCHEMBL12570644 | 0.78 | CCR4 (0.44) | MAPTSMN1; SMN2POLBPDGFRBPDGFRA | |
| SCHEMBL12570475 | 0.78 | PDGFRB (0.43) | MAPTSMN1; SMN2POLBPDGFRBPDGFRA | |
| SCHEMBL1491781 | 0.78 | MAPT (0.59) | MAPTSMN1; SMN2GAAPOLBCDK2 | |
| SCHEMBL14428206 | 0.78 | KMT2A (0.55) | MAPTSMN1; SMN2GAAPOLBCDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |
| US-20090047252-A1 | Antiviral compounds | GILEAD SCIENCES, INC. (US) | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090047252-A1 | Antiviral compounds | MAVS, EIF2AK2, ZC3HAV1 | MAPT 2923/4885SMN1; SMN2 1564/4885GAA 151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.