Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.57 |
| ▸ | GRM5 | P41594 | 2/20 | 0.54 |
| ▸ | NOS3 | P29474 | 1/20 | 0.53 |
| ▸ | NOS1 | P29475 | 1/20 | 0.53 |
| ▸ | NOS2 | P35228 | 1/20 | 0.53 |
| ▸ | DHFR | P00374 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1563917 | 0.89 | KCNH2 (0.73) | SMN1; SMN2KCNH2GRM5NOS1NOS2 | |
| SCHEMBL30173447 | 0.89 | KCNH2 (0.73) | SMN1; SMN2KCNH2GRM5NOS1NOS2 | |
| SCHEMBL3265299 | 0.80 | SMN1; SMN2 (0.81) | SMN1; SMN2GRM5KMT2A | |
| SCHEMBL13384818 | 0.80 | HRH1 (0.51) | SMN1; SMN2GRM5ALDH1A1CYP2D6LMNA | |
| SCHEMBL24916774 | 0.80 | CCR1 (0.52) | SMN1; SMN2KCNH2GRM5NOS3NOS1 | |
| SCHEMBL30201993 | 0.80 | CCR1 (0.52) | SMN1; SMN2KCNH2GRM5NOS3NOS1 | |
| SCHEMBL681574 | 0.79 | KCNH2 (0.64) | SMN1; SMN2KCNH2GRM5NOS3NOS1 | |
| SCHEMBL1563589 | 0.79 | SMN1; SMN2 (0.56) | SMN1; SMN2KCNH2GRM5POLBKMT2A | |
| SCHEMBL10144469 | 0.78 | KCNH2 (0.54) | SMN1; SMN2KCNH2GRM5NOS3NOS1 | |
| SCHEMBL14732969 | 0.77 | CCR1 (0.64) | SMN1; SMN2KCNH2GRM5NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120049167-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-01 | — | — | US | disclosed |
| US-20120049167-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-01 | — | — | US | disclosed |