Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | GRM5 | P41594 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 2/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | CCR8 | P51685 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1563917 | 1.00 | KCNH2 (0.73) | KCNH2SMN1; SMN2GRM5KDM4EALDH1A1 | |
| SCHEMBL10144374 | 0.89 | SMN1; SMN2 (0.59) | KCNH2SMN1; SMN2GRM5KDM4EALDH1A1 | |
| SCHEMBL24916774 | 0.87 | CCR1 (0.52) | KCNH2SMN1; SMN2GRM5NOS1KDM1A | |
| SCHEMBL30201993 | 0.87 | CCR1 (0.52) | KCNH2SMN1; SMN2GRM5NOS1KDM1A | |
| SCHEMBL10144469 | 0.85 | KCNH2 (0.54) | KCNH2SMN1; SMN2GRM5NOS1KDM1A | |
| SCHEMBL6559741 | 0.85 | KCNH2 (1.00) | KCNH2SMN1; SMN2ALDH1A1HPGDNOS1 | |
| SCHEMBL21999201 | 0.83 | TAAR1 (0.52) | KCNH2SMN1; SMN2NOS1NOS2BACE1 | |
| SCHEMBL1563589 | 0.82 | SMN1; SMN2 (0.56) | KCNH2SMN1; SMN2GRM5KDM4EALDH1A1 | |
| SCHEMBL8286835 | 0.80 | GRM5 (0.57) | KCNH2SMN1; SMN2GRM5KDM4ENOS1 | |
| SCHEMBL9447423 | 0.79 | NPSR1 (0.56) | KCNH2SMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115772058-B | Reduction method of aromatic internal olefins | 南通大学 | 2024-08-16 | — | — | CN | disclosed |
| CN-115772058-A | Reduction method of aromatic internal olefin | 南通大学 | 2023-03-10 | — | — | CN | disclosed |