Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR2 | O43603 | 14/20 | 1.00 |
| ▸ | GALR1 | P47211 | 9/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.58 |
| ▸ | GBA1 | P04062 | 1/20 | 0.57 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10144392 | 0.91 | GALR2 (1.00) | GALR2GALR1MEN1KMT2AMAPK1 | |
| SCHEMBL10143409 | 0.90 | GALR2 (0.82) | GALR2GALR1MEN1KMT2ANPC1 | |
| SCHEMBL10143587 | 0.90 | GALR2 (0.82) | GALR2GALR1MEN1KMT2ANPC1 | |
| SCHEMBL10143796 | 0.90 | GALR2 (1.00) | GALR2GALR1MEN1KMT2ANPC1 | |
| SCHEMBL10143418 | 0.85 | GALR2 (0.86) | GALR2GALR1MEN1KMT2ANPC1 | |
| SCHEMBL10144177 | 0.82 | GALR2 (0.82) | GALR2GALR1MEN1KMT2AMAPK1 | |
| SCHEMBL10144339 | 0.82 | GALR2 (0.82) | GALR2GALR1MAPK1TAAR1MAPT | |
| SCHEMBL10143593 | 0.82 | GALR2 (0.82) | GALR2GALR1MAPK1TAAR1MAPT | |
| SCHEMBL10144390 | 0.82 | GALR2 (0.81) | GALR2GALR1MAPK1TAAR1GBA1 | |
| SCHEMBL10143419 | 0.82 | GALR2 (0.81) | GALR2GALR1MAPK1TAAR1GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |