Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR2 | O43603 | 14/20 | 1.00 |
| ▸ | GALR1 | P47211 | 7/20 | 1.00 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10144392 | 0.93 | GALR2 (1.00) | GALR2GALR1TAAR1MAPK1KMT2A | |
| SCHEMBL10143418 | 0.93 | GALR2 (0.86) | GALR2GALR1TAAR1MAPK1KMT2A | |
| SCHEMBL10144388 | 0.90 | GALR2 (1.00) | GALR2GALR1TAAR1MAPK1KMT2A | |
| SCHEMBL10143549 | 0.87 | GALR2 (0.77) | GALR2GALR1TAAR1MAPK1KMT2A | |
| SCHEMBL10144339 | 0.87 | GALR2 (0.82) | GALR2GALR1TAAR1MAPK1MAPT | |
| SCHEMBL10143413 | 0.85 | GALR2 (1.00) | GALR2GALR1TAAR1MAPK1MAPT | |
| SCHEMBL10144177 | 0.85 | GALR2 (0.82) | GALR2GALR1TAAR1MAPK1KMT2A | |
| SCHEMBL10143419 | 0.84 | GALR2 (0.81) | GALR2GALR1TAAR1MAPK1ALDH1A1 | |
| SCHEMBL10143797 | 0.84 | GALR2 (0.83) | GALR2GALR1LMNANPSR1 | |
| SCHEMBL10144390 | 0.84 | GALR2 (0.81) | GALR2GALR1TAAR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |