Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 1.00 |
| ▸ | MEN1 | O00255 | 4/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 4/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | TP53 | P04637 | 7/20 | 0.77 |
| ▸ | MAPT | P10636 | 4/20 | 0.77 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | GALR3 | O60755 | 1/20 | 0.65 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15685952 | 0.84 | LMNA (1.00) | SMN1; SMN2MEN1KMT2ANPSR1CYP1A2 | |
| SCHEMBL28432040 | 0.83 | TSHR (0.76) | SMN1; SMN2MEN1KMT2ANPSR1CYP1A2 | |
| SCHEMBL7506833 | 0.83 | SMN1; SMN2 (0.71) | SMN1; SMN2MEN1KMT2ANPSR1CYP1A2 | |
| SCHEMBL29870044 | 0.83 | TSHR (0.76) | SMN1; SMN2MEN1KMT2ANPSR1CYP1A2 | |
| SCHEMBL15568033 | 0.81 | MEN1 (0.67) | SMN1; SMN2MEN1KMT2ANPSR1CYP1A2 | |
| SCHEMBL7970556 | 0.79 | GALR3 (1.00) | SMN1; SMN2MEN1KMT2ANPSR1CYP1A2 | |
| SCHEMBL8420520 | 0.79 | LMNA (0.73) | SMN1; SMN2MEN1KMT2ANPSR1CYP1A2 | |
| SCHEMBL15553033 | 0.79 | TSHR (0.69) | SMN1; SMN2MEN1KMT2ANPSR1CYP1A2 | |
| SCHEMBL228889 | 0.79 | LMNA (0.90) | SMN1; SMN2MEN1KMT2ANPSR1CYP1A2 | |
| SCHEMBL7508470 | 0.78 | NPC1 (0.74) | SMN1; SMN2MEN1KMT2ANPSR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014027053-A1 | BENZIMIDAZOLES FOR THE TREATMENT OF CANCER | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2014-02-20 | — | — | WO | claimed |
| WO-2014027053-A1 | BENZIMIDAZOLES FOR THE TREATMENT OF CANCER | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2014-02-20 | — | — | WO | disclosed |
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | BIOMARIN PHARMACEUTICAL INC. | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | ENGASE, GALNT1, GALNT13 | SMN1; SMN2 4780/4885MEN1 3791/4885KMT2A 1652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.