Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | HPGD | P15428 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.70 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | RAB9A | P51151 | 2/20 | 0.69 |
| ▸ | CA12 | O43570 | 1/20 | 0.64 |
| ▸ | CA1 | P00915 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | CA9 | Q16790 | 1/20 | 0.64 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | KLK7 | P49862 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2453779 | 0.96 | SMN1; SMN2 (0.78) | SMN1; SMN2LMNAMEN1KMT2AHPGD | |
| SCHEMBL30034264 | 0.89 | SMN1; SMN2 (0.88) | SMN1; SMN2LMNAMEN1KMT2AHPGD | |
| SCHEMBL9923545 | 0.87 | RAB9A (0.71) | SMN1; SMN2LMNAMEN1KMT2AHPGD | |
| SCHEMBL16542117 | 0.84 | SMN1; SMN2 (0.83) | SMN1; SMN2LMNAMEN1KMT2AHPGD | |
| SCHEMBL13185621 | 0.84 | SMN1; SMN2 (1.00) | SMN1; SMN2LMNAMEN1KMT2AHPGD | |
| SCHEMBL3923158 | 0.84 | SMN1; SMN2 (0.78) | SMN1; SMN2LMNAMEN1KMT2AHPGD | |
| SCHEMBL13984251 | 0.82 | SMN1; SMN2 (0.76) | SMN1; SMN2LMNAMEN1KMT2AHPGD | |
| SCHEMBL5659226 | 0.82 | SMN1; SMN2 (0.76) | SMN1; SMN2LMNAMEN1KMT2AHPGD | |
| SCHEMBL29769748 | 0.82 | SMN1; SMN2 (0.76) | SMN1; SMN2LMNAMEN1KMT2AHPGD | |
| SCHEMBL27432885 | 0.82 | GAA (0.76) | SMN1; SMN2LMNAMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | BIOMARIN PHARMACEUTICAL INC. | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | ENGASE, GALNT1, GALNT13 | SMN1; SMN2 4780/4885LMNA 4109/4885MEN1 3791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.