Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10106371 | 0.96 | NPC1 (0.31) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10330559 | 0.94 | — | — | |
| SCHEMBL10106372 | 0.88 | NPC1 (0.34) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10145047 | 0.88 | FFAR1 (0.31) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10145164 | 0.87 | NTSR1 (0.32) | — | |
| SCHEMBL10106311 | 0.87 | NPC1 (0.34) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10106377 | 0.87 | NPC1 (0.34) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10330563 | 0.86 | FFAR1 (0.30) | — | |
| SCHEMBL10145090 | 0.85 | — | — | |
| SCHEMBL10330583 | 0.85 | NTSR1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8202896-B2 | Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases | MICRODOSE THERAPEUTX, INC. (US) | 2012-06-19 | — | — | US | disclosed |