Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 5/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10186973 | 0.81 | TAAR1 (0.61) | AOC3TAAR1SIGMAR1SLC6A2 | |
| SCHEMBL8084282 | 0.76 | TAAR1 (0.55) | AOC3TAAR1SIGMAR1 | |
| SCHEMBL8817598 | 0.76 | AOC3 (1.00) | AOC3TAAR1SIGMAR1 | |
| Demelverine SCHEMBL1516521 | 0.75 | SIGMAR1 (0.76) | AOC3TAAR1SIGMAR1SLC6A2 | |
| SCHEMBL22863888 | 0.75 | TAAR1 (1.00) | AOC3TAAR1SIGMAR1 | |
| SCHEMBL168948 | 0.75 | TAAR1 (1.00) | AOC3TAAR1SIGMAR1 | |
| SCHEMBL13428484 | 0.75 | AOC3 (0.55) | AOC3TAAR1SIGMAR1SLC6A2 | |
| Hydrochloric Acid SCHEMBL17064263 | 0.74 | AOC3 (0.95) | AOC3TAAR1SIGMAR1 | |
| SCHEMBL9768687 | 0.73 | SIGMAR1 (0.73) | AOC3TAAR1SIGMAR1SLC6A2 | |
| Hydrochloric Acid SCHEMBL4354648 | 0.73 | TAAR1 (0.95) | AOC3TAAR1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2415765-A1 | PYRIMIDINE COMPOUND | Astellas Pharma Inc. (JP) | 2012-02-08 | — | — | EP | disclosed |