Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 19/20 | 0.39 |
| ▸ | CNR1 | P21554 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13618561 | 0.88 | ALDH1A1 (0.34) | KDM4EALDH1A1LMNAHPGDTSHR | |
| SCHEMBL352500 | 0.76 | HDAC4 (0.41) | CNR2CNR1 | |
| SCHEMBL352122 | 0.74 | CNR2 (0.43) | CNR2CNR1 | |
| SCHEMBL351388 | 0.72 | CNR2 (0.44) | CNR2CNR1 | |
| SCHEMBL10146116 | 0.70 | CYP1A2 (0.37) | ALDH1A1CNR2 | |
| SCHEMBL9344850 | 0.69 | CNR2 (0.48) | KDM4EALDH1A1LMNAHPGDTSHR | |
| SCHEMBL31375602 | 0.69 | NPC1 (0.54) | KDM4EALDH1A1LMNAHPGDTSHR | |
| SCHEMBL20043166 | 0.69 | CNR2 (0.48) | CNR2CNR1 | |
| SCHEMBL10146108 | 0.68 | PIK3CG (0.44) | KDM4EALDH1A1HPGDHSD17B10CNR2 | |
| SCHEMBL77622 | 0.67 | NR1H4 (0.57) | KDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120015988-A1 | Sulfone Compounds Which Modulate The CB2 Receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-01-19 | — | — | US | disclosed |
| US-20120015988-A1 | Sulfone Compounds Which Modulate The CB2 Receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015988-A1 | Sulfone Compounds Which Modulate The CB2 Receptor | CNR2, CNR1, TRPV1 | KDM4E 2157/4885ALDH1A1 2844/4885LMNA 4742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.