SCHEMBL1014646

SCHEMBL1014646

CCOC(=O)CC(=O)C1CC1

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.58
MGAM O43451 1/20 0.58
SI P14410 1/20 0.58
MGAM2 Q2M2H8 1/20 0.58
ALDH1A1 P00352 4/20 0.43
TRPA1 O75762 1/20 0.43
SOAT1 P35610 1/20 0.41
RAB9A P51151 1/20 0.40
SMYD3 Q9H7B4 1/20 0.39
ALOX15 P16050 1/20 0.39
KMT2A Q03164 1/20 0.39
EPHX2 P34913 1/20 0.38
CYP1A2 P05177 1/20 0.38
RECQL P46063 1/20 0.37
LMNA P02545 1/20 0.37
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2005270 0.92 GAA (0.54) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL1617817 0.92 GAA (0.54) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL4997648 0.91 GAA (0.48) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL10236626 0.91 GAA (0.51) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL2680543 0.91 GAA (0.51) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL434421 0.90 MGAM (0.52) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL8269713 0.88 GAA (0.45) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL4480984 0.88 GAA (0.45) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL13848940 0.87 GAA (0.48) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL6890748 0.87 GAA (0.48) GAAMGAMSIMGAM2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 670 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250075147-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NEW FLAVOR AND FRAGRANCE INGREDIENTS OSMO LABS, PBC 2025-03-06 US claimed
EP-4747245-A1 PHARMACEUTICAL COMPOUNDS Almac Discovery Limited (GB) 2026-05-27 EP disclosed
WO-2026104998-A1 SUBSTITUTED IMIDAZOPYRIDINE COMPOUND DERIVATIVES AND THEIR PHARMACEUTICAL USE AVELOS THERAPEUTICS INC. (KR) 2026-05-21 WO disclosed
EP-4735430-A1 MALT1 INHIBITORS Janssen Pharmaceutica NV (BE) 2026-05-06 EP disclosed
EP-4720058-A2 BIFUNCTIONAL DEGRADERS AND USES THEREOF Casma Therapeutics, Inc. (US) 2026-04-08 EP disclosed
EP-4720067-A1 BICYCLIC HETEROARYLAMIDES HAVING GPR68 MODULATING ACTIVITY Recursion Pharmaceuticals, Inc. (US) 2026-04-08 EP disclosed
EP-4707276-A2 MALT1 MODULATORS AND USES THEREOF Rarefied Biosciences, Inc. (US) 2026-03-11 EP disclosed
US-12558341-B2 Oral complement factor D inhibitors BIOCRYST PHARMACEUTICALS, INC. (US) 2026-02-24 US disclosed
EP-4499611-B1 MALT1 MODULATORS AND USES THEREOF RAREFIED BIOSCIENCES INC (US) 2026-02-18 EP disclosed
EP-4691553-A2 FXR (NR1H4) MODULATING COMPOUNDS Gilead Sciences, Inc. (US) 2026-02-11 EP disclosed
US-5075316-A For plants CIBA-GEIGY CORPORATION (US) 1991-12-24 US disclosed
EP-0444533-A2 Quinoline and pyridine anchors for HMG-CoA reductase inhibitors E.R. SQUIBB & SONS, INC. (US) 1991-09-04 EP disclosed
US-5032602-A Inhibiting HMG-CoA reductase with novel substituted 2-pyridones and pyrid-2-thiones BAYER AKTIENGESELLSCHAFT (DE) 1991-07-16 US disclosed
US-5006530-A Certain 7-[2,6-diisopropyl-4-phenyl-5-lower alkoxymethyl-pyrid-3-yl]-3,5-dihydroxy-6-enoates and derivatives useful for treating circulatory diseases BAYER AKTIENGESELLSCHAFT (DE) 1991-04-09 US disclosed
US-4968689-A Certain 2,6-diisopropyl-4-(4-fluoro-phenyl)-3,5-bis-dimethyl-3',5'-dihydroxy-hept-6-enoate-pyridine derivatives useful for treating lipoproteinaemia and arteriosclerosis BAYER AKTIENGESELLSCHAFT (DE) 1990-11-06 US disclosed
EP-0388838-A2 Parasiticide CIBA-GEIGY AG (CH) 1990-09-26 EP disclosed
US-4935434-A Antiarthritic isoxazole-4-carboxamides BRISTOL-MYERS COMPANY (US) 1990-06-19 US disclosed
EP-0326107-A1 Antiarthritic beta-cycloalkyl-beta-oxopropionitriles Bristol-Myers Squibb Company (US) 1989-08-02 EP disclosed
EP-0326108-A1 Antiarthritic isoxazole-4-carboxamides Bristol-Myers Company (US) 1989-08-02 EP disclosed
US-4500541-A Pharmacologically active cyclopropane derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1985-02-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12558341-B2 Oral complement factor D inhibitors CFD, CFH, CFB GAA 2438/4885MGAM 2346/4885SI 1098/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.