Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL654562 | 0.78 | NPY5R (0.45) | DGAT1SIGMAR1NPY5RMAPTTDP1 | |
| SCHEMBL3842297 | 0.78 | AVPR1A (0.50) | TDP2OPRD1SIGMAR1NPY5RTDP1 | |
| SCHEMBL738397 | 0.78 | AVPR1A (0.50) | SIGMAR1NPY5RMAPT | |
| Hydrochloric Acid SCHEMBL6820620 | 0.77 | AVPR1A (0.49) | SIGMAR1NPY5RMAPT | |
| SCHEMBL29674557 | 0.76 | SIGMAR1 (0.54) | SIGMAR1NPY5R | |
| SCHEMBL171980 | 0.76 | SIGMAR1 (0.54) | SIGMAR1NPY5R | |
| SCHEMBL736532 | 0.75 | AVPR1A (0.53) | OPRD1KCNH2SIGMAR1NPY5RALDH1A1 | |
| Hydrochloric Acid SCHEMBL2002554 | 0.74 | SIGMAR1 (0.52) | SIGMAR1NPY5R | |
| Hydrochloric Acid SCHEMBL20955204 | 0.74 | AVPR1A (0.52) | OPRD1KCNH2SIGMAR1NPY5RALDH1A1 | |
| SCHEMBL30591620 | 0.73 | KDM4E (0.43) | TDP2POLBKMT2ASRD5A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009217-A1 | SPIROCYCLIC COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2012-01-19 | — | — | WO | disclosed |